Download A Textbook of Clinical Pharmacology and Therapeutics Fifth Version by James M Ritter, Lionel D Lewis, Timothy Gk Mant and Albert Ferro PDF free.


E-book Particulars :
Language English
Pages 476
Format PDF
Dimension 4.06 MB

A Textbook of Clinical Pharmacology and Therapeutics Fifth Version by James M Ritter

Book Description:

If you understand how drugs work (pharmacodynamics), how they are handled by the body (pharmacokinetics), how they interact with each other, and how drug treatments are assessed, then you will become a better prescriber. A Textbook of Clinical Pharmacology and Therapeutics gives you that understanding. Fully revised throughout and extensively illustrated, the fifth edition of this well-established textbook has been streamlined to focus on what medical students and junior doctors really need to know in order to understand the implications of prescribing one drug over, or in combination with, another. The text provides current information on all areas of drug prescribing with updated discussion and guidance on such topics as adverse drug reactions, personalized medicine, gene and cell-based therapy, advances in cancer therapy, and mechanisms of drug action and treatment guidelines in HIV and mycobacterial infections therapy. A new chapter on alternative medicines and nutraceuticals has been introduced and Further Reading lists have been updated to include key medical websites. All medical students and junior doctors who read this book will learn not only how to use drugs safely and effectively, but, importantly, the rationale behind effective prescribing decisions.


PREFACE of Textbook of Clinical Pharmacology and Therapeutics:

Clinical pharmacology is the science of drug use in people. Clinicians of all specialties prescribe medicine each day, and that is each one of essentially the most helpful but in addition one of essentially the most harmful actions of our skilled lives.

Understanding the rules of scientific pharmacology is the premise of protected and efficient therapeutic observe, which is why this topic types an more and more essential half of the medical curriculum.

This textbook is addressed primarily to medical college students and junior docs of all specialties, but in addition to different professionals who more and more prescribe medicines (together with pharmacists, nurses and another allied professionals).

Clinical pharmacology is a fast-paced topic and the current version has been fully revised and up to date. It differs from the fourth version in that it concentrates solely on points that college students ought to know and perceive, moderately than together with so much of reference materials.

This has enabled us to maintain its size down. One other characteristic has been to incorporate many new illustrations to help in greedy mechanisms and rules.

The primary part offers with basic rules together with pharmacodynamics, pharmacokinetics and the varied components that modify drug disposition and drug interplay. We’ve stored algebraic formulations to a minimal.

Drug metabolism is approached from a sensible viewpoint, with dialogue of the thrilling new idea of personalised medication.

Opposed drug reactions and the use of medicine on the extremes of age and in being pregnant are lined, and the introduction of new medicine is mentioned from the point of view of college students who will see many new remedies launched throughout their skilled careers.

Many sufferers use natural or different various medicines and there’s a new chapter on this essential subject. There’s a chapter on gene and cell-based therapies, that are simply starting to enter scientific observe.

The remaining sections of the guide deal comprehensively with main methods (nervous, musculoskeletal, cardiovascular, respiratory, alimentary, renal, endocrine, blood, pores and skin and eye) and with multi-system points together with remedy of infections, malignancies, immune illness, habit and poisoning.

 

A Textbook of Clinical Pharmacology and Therapeutics

Author(s): James M Ritter, Lionel D Lewis, Timothy GK Mant, Albert Ferro

Series: A Hodder Arnold Publication

Publisher: Oxford University Press, USA, Year: 2008

ISBN: 9780340900468

[PDF] A Textbook of Clinical Pharmacology and Therapeutics by James M Ritter Table Of Contents

Book title……Page 4
CONTENTS……Page 8
FOREWORD……Page 9
PREFACE……Page 10
ACKNOWLEDGEMENTS……Page 11
PART I: GENERAL PRINCIPLES……Page 12
1 Introduction to therapeutics……Page 14
2 Mechanisms of drug action (pharmacodynamics)……Page 17
3 Pharmacokinetics……Page 22
4 Drug absorption and routes of administration……Page 28
5 Drug metabolism……Page 35
6 Renal excretion of drugs……Page 42
7 Effects of disease on drug disposition……Page 45
8 Therapeutic drug monitoring……Page 52
9 Drugs in pregnancy……Page 56
10 Drugs in infants and children……Page 63
11 Drugs in the elderly……Page 67
12 Adverse drug reactions……Page 73
13 Drug interactions……Page 82
14 Pharmacogenetics……Page 90
15 Introduction of new drugs and clinical trials……Page 97
16 Cell-based and recombinant DNA therapies……Page 103
17 Alternative medicines: herbals and nutraceuticals……Page 108
PART II: THE NERVOUS SYSTEM……Page 114
18 Hypnotics and anxiolytics……Page 116
19 Schizophrenia and behavioural emergencies……Page 121
20 Mood disorders……Page 127
21 Movement disorders and degenerative CNS disease……Page 135
22 Anti-epileptics……Page 144
23 Migraine……Page 153
24 Anaesthetics and muscle relaxants……Page 156
25 Analgesics and the control of pain……Page 166
PART III: THE MUSCULOSKELETAL SYSTEM……Page 176
26 Anti-inflammatory drugs and the treatment of arthritis……Page 178
PART IV: THE CARDIOVASCULAR SYSTEM……Page 186
27 Prevention of atheroma: lowering plasma cholesterol and other approaches……Page 188
28 Hypertension……Page 196
29 Ischaemic heart disease……Page 207
30 Anticoagulants and antiplatelet drugs……Page 215
31 Heart failure……Page 222
32 Cardiac dysrhythmias……Page 228
PART V: THE RESPIRATORY SYSTEM……Page 242
33 Therapy of asthma, chronic obstructive pulmonary disease (COPD) and other respiratory disorders……Page 244
PART VI: THE ALIMENTARY SYSTEM……Page 256
34 Alimentary system and liver……Page 258
35 Vitamins and trace elements……Page 276
PART VII: FLUIDS AND ELECTROLYTES……Page 282
36 Nephrological and related aspects……Page 284
PART VIII: THE ENDOCRINE SYSTEM……Page 294
37 Diabetes mellitus……Page 296
38 Thyroid……Page 303
39 Calcium metabolism……Page 308
40 Adrenal hormones……Page 313
41 Reproductive endocrinology……Page 318
42 The pituitary hormones and related drugs……Page 327
PART IX: SELECTIVE TOXICITY……Page 332
43 Antibacterial drugs……Page 334
44 Mycobacterial infections……Page 345
45 Fungal and non-HIV viral infections……Page 351
46 HIV and AIDS……Page 362
47 Malaria and other parasitic infections……Page 372
48 Cancer chemotherapy……Page 378
PART X: HAEMATOLOGY……Page 398
49 Anaemia and other haematological disorders……Page 400
PART XI: IMMUNOPHARMACOLOGY……Page 408
50 Clinical immunopharmacology……Page 410
PART XII: THE SKIN……Page 420
51 Drugs and the skin……Page 422
PART XIII: THE EYE……Page 432
52 Drugs and the eye……Page 434
PART XIV: CLINICAL TOXICOLOGY……Page 442
53 Drugs and alcohol abuse……Page 444
54 Drug overdose and poisoning……Page 455


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