Molecular Cell Biology By Lodish et al
Book Excerpt
Modern biology is rooted in an understanding of the molecules within cells and of the interactions between cells that allow construction of multicellular organisms. The more we learn about the structure, function, and development of different organisms, the more we recognize that all life processes exhibit remarkable similarities. Molecular Cell Biology concentrates on the macromolecules and reactions studied by biochemists, the processes described by cell biologists, and the gene control pathways identified by molecular biologists and geneticists. In this millennium, two gathering forces will reshape molecular cell biology: genomics, the complete DNA sequence of many organisms, and proteomics, a knowledge of all the possible shapes and functions that proteins employ.
All the concepts of molecular cell biology continue to be derived from experiments, and powerful experimental tools that allow the study of living cells and organisms at higher and higher levels of resolution are being developed constantly. In this fourth edition, we address the current state of molecular cell biology and look forward to what further exploration will uncover in the twenty-first century.
Book Contents
About the Authors
Preface
Acknowledgments
Supplements
1. The Dynamic Cell
2. Chemical Foundations
3. Protein Structure and Function
4. Nucleic Acids, the Genetic Code, and the Synthesis of Macromolecules
5. Biomembranes and the Subcellular Organization of Eukaryotic Cells
6. Manipulating Cells and Viruses in Culture
7. Recombinant DNA and Genomics
8. Genetic Analysis in Cell Biology
9. Molecular Structure of Genes and Chromosomes
10. Regulation of Transcription Initiation
11. RNA Processing, Nuclear Transport, and Post-Transcriptional Control
12. DNA Replication, Repair, and Recombination
13. Regulation of the Eukaryotic Cell Cycle
14. Gene Control in Development
15. Transport across Cell Membranes
16. Cellular Energetics: Glycolysis, Aerobic Oxidation, and Photosynthesis
17. Protein Sorting: Organelle Biogenesis and Protein Secretion
18. Cell Motility and Shape I: Microfilaments
19. Cell Motility and Shape II: Microtubules and Intermediate Filaments
20. Cell-to-Cell Signaling: Hormones and Receptors
21. Nerve Cells
22. Integrating Cells into Tissues
23. Cell Interactions in Development
24. Cancer
Glossary
